When Marissa, the daughter of Adrienne Shapiro, was diagnosed with sickle cell disease, the doctors said she was not going to survive until her first birthday. However, it did not mean the end of Adrienne’s worries when Marissa continued to survive beyond the benchmark. It was actually the beginning of several excruciating years of transfusions of blood and immunological disorders. Marissa was unable to undergo further blood transfusions after a serious reaction caused by an incorrectly mixed blood transfusion resulted in the removal of her gall bladder and temporary kidney failure.Learn more by visiting San Antonio knee pain treatment
Luckily, however, a project funded by the California Institute for Regenerative Medicine (CIRM), led by Don Kohn, MD at UCLA, started a clinical trial for Marissa. The project’s aim was to “remove the patient’s bone marrow and correct the genetic defect in the blood-forming stem cells.” Then, to establish a new, balanced blood supply, those cells can be reintroduced into the patient.’ Adrienne is optimistic that, due to the success of this clinical trial, her daughter will be able to live a safe and pain-free life with the aid of regenerative medicine.
‘Regenerative Medicine,’ according to the Stem Cell & Regenerative Medicine Center at the University of Wisconsin-Madison, is a “new scientific and medical field focused on harnessing the power of stem cells and the body’s own regenerative capabilities to restore function to damaged cells, tissues, and organs.”
Stem cells that are present in newborn children’s umbilical cord blood have the potential to renew and replace themselves. A stem cell can differentiate to become a specialised cell like a brain cell or a muscle cell, or it can stay a stem cell, due to the mechanism of mitosis. They can also restore internal damage caused by any illness, disorder or trauma of any sort. These cells are used to treat diseases and illnesses in a number of ways, including stem cell transplantation, stem cell grafting, and regenerative medicine.
Biochemistry, genetics, molecular biology, and immunology are among the scientific disciplines that make up regenerative medicine. In this area, scientists from these fields have carried out research and studies and established three methods of using regenerative medicine. There are cellular therapies, tissue engineering, and artificial organs and medical devices.
Cellular Therapies – This technique is used to remove and preserve cellular products, often adult stem cells, and then inject them into the site of injury, tissue damage or disease. These cells then fix or regenerate new cells to replace the ones that have been damaged.
Tissue Engineering – This technique is linked to the production of biomaterials and utilises a mixture of functional tissues, cells and scaffolds to engineer a fully functioning organ that is then inserted instead of a damaged organ or tissue into the receiver’s body.
Medical Devices and Artificial Organs – When a body organ fails, replacing it with a donor organ is the most effective form of care. Donor organs are scarce and can be a stumbling block in such circumstances. Even if a suitable donor is found, he or she will be expected to take immunosuppressive drugs prior to the transplant, which have been known to cause side effects. In such cases, instead of transplantation, medical devices that replicate the function of the failed organ can be used. The ventricular assist system (VAD) that is used in lieu of heart transplants is an instance of one such device.